New beginning for Spider-Man began in the popular Ultimate Spider-Man comic book series. Re-imagined for the new century! Series lasted 133 issues until it is redesigned to Ultimate Comics Spider-Man with a new number 1.

The return of the most dangerous enemies of Spider-Man: Venom! The sinister symbiote selects a new owner, Harry Osborn! Spider can save his best friend when COMMANDER rage gave orders to kill Venom ... once and for all!