It has been two years since the Master’s plan succeeded and a near apocalypse coated the world in eternal darkness. Now able to roam freely, the Master’s legion of vampires rule the world—a horrifying police state where humans are harvested for blood. As humanity despairs, Dr. Ephraim Goodweather and an unlikely team of heroes continue their

When a Boeing 777 lands at JFK International Airport and goes dark on the runway, the Centers for Disease Control, fearing a terrorist attack, calls in Dr. Ephraim Goodweather and his team of expert biological-threat first responders. Only an elderly pawnbroker from Spanish Harlem suspects a darker purpose behind the event—an ancient threat

As the CDC's Dr. Ephraim Goodweather makes one last attempt to stop the swiftly moving vampire plague, he sends those dearest to him away from the city—a decision the doctor will soon regret. Meanwhile, a ragtag gang of street fighters joins forces with an elderly pawnbroker to secure an ancient tome that may tip the scales in this ongoing war.

Unable to kill the Master—the powerful vampire behind the epidemic infesting New York City—Dr. Ephraim Goodweather begins to self-destruct as battle lines are drawn. It’s now up to a handful of humans—an ailing pawnbroker, an exterminator, a scientist, a gangbanger, and an alcoholic—to stop an ancient evil from devouring the human race!

A vast conspiracy has made it nearly impossible for the CDC’s Dr. Ephraim Goodweather to convince the world that there’s a vampiric epidemic spreading across Manhattan. His only hope is to go head to head with the ancient evil responsible for the wave of bloodthirsty vamps set to drown the Big Apple . . . but can the strain be stopped?!